The study of the emergence and spread of bacterial strains that cause infectious diseases and are resistant to antibiotics. Development of modern alternative approaches to antimicrobial therapy through targeting bacterial virulence and adhesion.

A modern alternative approach to antimicrobial therapy is targeting bacterial virulence and specifically adhesion as one of virulence factors. Modern strategies for anti-adhesion therapy, the mechanisms of inhibition pathogen adherence, immunization.

Anti-inflammatory properties of SnCl4 with benzaldehyde and 4-bromobenzaldehyde salicyloyl hydrazones the were studied in the rats using models on carrageenan and formalin-induced inflammation of paw. The anti-inflammatory activity in both models.

The search for new effective methods of effective therapeutic effect in order to improve the quality and increase the life expectancy of patients with coronary heart disease. A study of a polyphenols - resveratrol for the treatment of patients with CHD.

Study of anti-remodeling effectiveness of complex pharmacotherapy to patients with chronic heart failure and metabolic syndrome using perindopril, spironolactone and bisoprolol. Anti-remodeling efficacy of the combined use of the studied drugs.

Influence of antiviral properties of titanium nanoparticles on the reproduction of plant and animal viruses. Form of nanoparticles in preparations. Their antiviral activity against virus strains according to preventive, therapeutic and virucidal schemes.

The pharmacodynamic effects of niftolide and other androgen receptor antagonists from the group of substituted carboxanilides that had been synthesized locally were studied. Development of new methods for treatment of androgen-dependent prostate cancer.

The use of bioactive compounds in the treatment of bacterial infections. Evaluation of the antibacterial potential of the ethanolic extract obtained from the leaves of F. lingua. Study of the effect of alkaloids on gram-positive and gram-negative strains.

Понятие антибиотиков и их использование в медицине. Тест на чувствительность бактерий к ним. Целебные свойства серебра. Содержание антибиотиков в питьевой воде и молоке. История получения пенициллина. Проблема антибиотикоустойчивости микроорганизмов.

Principles of antibiotic prophylaxis. Surgical antibiotic prophylaxis. Prevention of metastatic bacteremias. Antibiotic prophylaxis and varied clinical situations. Bacterial endocarditis. Orthopedic prosthetic joints. Immunocompromised patients.

Risk assessment and factors that can negatively influence the consumers’ health. The implementation of norms and standards of new antimicrobial medicinal product registration in the Ukraine. Antibiotic resistantce as risk assessment component for human.

Definition of mood disorders, impact on a global scale and unmet needs. Causes and associations in mood disorders: genetics and pharmacogenetics. Clinical diagnosis and assessment of schizophrenia. Antipsychotic drugs and atypical antipsychotics.

The search for new and effective antimicrobial and antifungal agents is an important task of medical chemistry. The results of microbiological screening of new derivatives of [1,2,4]triazolo[4,3-a]pyrazine. Increased exposure to the microbial cell.

Evaluation of the effectiveness of therapeutic plasmapheresis (TP) in the complex treatment of patients with peritoneal endometriosis, infertility and point mutations in the NAT2 gene. The effectiveness of the treatment: laparoscopy and the course of TP.

The activity of nitrate- [4- (3,4-dimethyl, -phenyl) -2- (2-oxo-3-methoxybenzylidene) hydrazinecarbothioamido] copper (CDI-14) new biochemical complex of the thiosemicarbazonate class, inhibit the growth of epithelial cells of two cancerous lines.

Genital herpes - one of the most socially important problem in clinical practice of dermatovenereologist, obstetrician-gynecologists. Antivirals of systemic effect and local action for herpetic infection therapy on pharmaceutical market of Ukraine.

The rationale and techniques for treatment of the non-vital immature tooth. The treatment of choice for necrotic teeth is apexification, which is induction of apical closure to produce more favorable conditions for conventional root canal filling.

The purpose of this in vitro study was to investigate the canal configuration types, and the prevalence and location of anatomical variations in the mesiobuccal and mesial roots of permanent maxillary and mandibular first molars after instrumentation.

Creation of an antitumor drug based on biologically active substances of wormwood. Possibility of using the drug in the complex treatment of oncological diseases. Clinical determination of living cells by fluorescence spectroscopy.

Studying of comorbid conditions. The arterial hypertension and chronic obstructive pulmonary disease. Oscillation blood pressure worsen the prognosis, and difficulties in choosing treatment remain a serious problem in the management of patients.

Abnormally prolonged dwell time of acidic gastric contents in the oesophagus. The injurious effects of gastric acid are central to the pathogenic process of oesophagitis. Patterns of Gastro-Oesophageal Reflux. Medical Treatment of Reflux Oesophagitis.

The search for innovative approaches to the treatment of blood diseases. Investigation of platelet aggregation of the vaginal woman. Extraction of an antiplatelet agent from the snake Echis multisquamatis. Clinical testing of ADP aggregation models.

Assessment of the impact of coronavirus infection on the development and spread of arrhythmias. Age and excess body weight as risk factors for arrhythmia after coronavirus infection. Analysis of the frequency of paroxysms, prerequisites for its increase.

Морфофункциональная классификация суставов. Мышцы, обеспечивающие движения в суставе, соединение костей конечностей. Степень подвижности костей, которая зависит от толщины прослойки соединяющей их ткани. Образование синовиальной мембраны и хрящевой ткани.

Hair transplant in cosmetic surgery as an art. Maintaining the correct angle and direction of hair follicles during graft implantation to achieve maximum density and natural results. Study of the role of alopecia in work and interpersonal relationships.

Study of the opinion of geriatric patients about the received health care in the hospital, the conditions for improving the quality of nursing care in hospital departments. Evaluation of the activities of nursing staff of hospitals in the city of Plovdiv.

Learning the optimal nutritional status. Consideration of the concept of the dietary assesment, as a comprehensive evaluation of a person's food intake. Estimating average intake of nutrients. Familiarization with nutritional deficiency diseases.

The main symptoms of biliary tract dyskinesia. The presence of pain in the upper part of the abdomen, mainly on the right side. Significant differences in domains of quality of life between patients with gallbladder dyskinesia and healthy individuals.

Comprehensive neurotoxic risk assessment of nitrogen-doped multilayer graphene. Analysis of the possibility of interaction with heavy metals in the biological system N-MLG. Use of a Cd2+/Pb2+/Hg2+-induced acute neurotoxicity model in nerve terminals.

Frequency of complement deficiency in patients with meningococcal disease in the Netherlands from 1959 through 1992. Studies pedigree for identifying those complement-deficient persons who require vaccination. The annual rate of meningococcal disease.