Given the presence of antimicrobial activity for tetrazole derivatives and its condensed analogues, it was proposed to analyze 13 novel 5-phenyl-5,6-dihydrotetrazolo[1,5- c]quinazolines for molecular docking to ribosomal in comparison with Tedizolid.

Structural formula of Tedizolid as antimicrobial and structural analogue and proposed 5-phenyl-5,6-dihydrotetrazolo[1,5-c]quinazolines. Affinity to binding sites of 2QEX, with decreasing of score. Descriptives of formed bonds to 50S ribosomal protein L2P.

Microscopic fungi including yeasts are important part of human microbiota. The molecular genetic identification of human sputum yeast isolate MF22_1, belonging to Candida spp., by using multiple genetic markers including ribosomal operon regions.

Non-adjuvant polychemotherapy - technology that indicates the presence of chemo-resistant tumor cells. Molecular-biological markers of tumors - certain chromosomal and gene mutations that involved in the development, progression of malignant diseases.

A stable antibody which can be used over a period of time. Extract mouse tumour cells, which grow continuously, and culture them in the laboratory. Analizes of immune response to monoclonal antibodies produced in mice, as these are foreign proteins.

Study of the structure of neurons in the anterior horns of the spinal cord in PIPN with the introduction of 2-ethyl-6-methyl-3-hydroxypyridine succinate. Metabolic effect of correction of morphofunctional state of spinal cord motoneurons in white rats.

Features of morphostructural changes in the uterus of rats with prevailing hemodynamics disorder of the organ in NNLA-injection. Microcirculatory changes as a manifestation of vascular decompensation, accompanied by disturbances of blood rheology, etc.

Combined impedance monitoring in patients with gastroesophageal reflux. Functional disorders of the esophagus in patients with proton pump inhibitor deficiency. Comparative characteristics of reflux between respondents and nonresponders receiving PPI.

Analysis of the medical and social problem of rheumatoid arthritis. The nature of the course of the disease, the main lesions of the musculoskeletal system. The effectiveness of exercise during the rehabilitation of patients with rheumatoid arthritis.

Tongue piercing and associated dental complications. The case presented here draws attention to the possibility of multiple tooth fracture as a result of trauma incurred from a barbell inserted into the tongue: systemic complications of this practice.

Определение серотипов, генотипов и резистентности к антимикробным препаратам штаммов Streptococcus pneumoniae, полученных от здоровых детей и детей с различными формами пневмококковой инфекции. Пути преодоления резистентности в современных условиях.

Definition, the basic physical and chemical properties, advantages and possibilities of application of nano-emulsions in the pharmaceutical, cosmetic, food, chemical industries. Characteristics of the methods and mechanisms for obtaining nanoemulsions.

To study the prospects of using nanoemulsion in the modern pharmaceutical industry. Bioavailability of colloidal solutions. The ability of the solubility of nanoemulsions and their ability to protect drugs from hydrolysis and enzymatic degradation.

Investigate a possible role of the polymorphisms by comparing the distribution of genotypes in the control group and in patients with type two diabetes mellitus and retinopathy. Analysis of the reasons for the increase in the frequency of heterozygotes.

Генетические факторы, вовлеченные в патогенез болезни Паркинсона. Анализ "нейродегенеративных панелей". Верификация отдельных вариантов с помощью секвенирования по Сенгеру. Использование современных технологий полногеномного ассоциативного анализа.

Adaptation to eugenol and citral by exposure of pathogens to increasing concentrations of essential oils. Determination of antibiotic susceptibility. Evaluation of the effect of eugenol and citral on the adherence ability by the crystal violet assay.

Вплив циркулюючих імунних комплексів на ультраструктурні особливості клітин. Корекція функціонально-структурних порушень, зумовлених хронічною гіперімунокомплексемією, за допомогою корвітину. Синтез оксиду азоту у тканинах печінки та ендотеліоцитах.

Исследовались особенности осмотической резистентности тромбоцитов, подвергнутых преинкубации с донатором оксида азота (нитропруссидом натрия) в конечной концентрации. Оценивалось изменение количества свободных клеток и агрегатов, их размеров и формы.

Дослідження активності ензимів окисного шляху метаболізму L-аргініну в лімфоцитах периферичної крові хворих на реактивний артрит. Вивчення кінетичних властивостей NO-синтаз. Оптимальні умови функціонування ендотеліальної та індуцибельної NO-синтаз.

Apical periodontitis is a disease of root canal infection. The etiology of post-treatment apical periodontitis. Exogenous materials causing foreign body reaction at the periapex. Endogenous substances and foreign body reaction. Biology of cholesterol.

Analysis of the study of colorectal motility in humans and disorders found in constipation with slow transit. The main characteristic of motor activity of the colon. Peculiarity of detecting specialized distributed activity with driving properties.

General population who get epistaxis. Types and categories of nosebleeds. Pathophysiological process in the nose. First aid for bleeding. The main causes of the disease. The risk factors. The drugs for medical treatment of epistaxis. Surgical emergency.

Аналіз ролі пероксинітриту в репаративній регенерації кісткової тканини нижньої щелепи після моделювання її перелому на тлі надмірного надходження в організм нітрату натрію. Дослідження складу органічного і мінерального компонентів кісткової тканини.

Дослідження біохімічного стану сполучної тканини та морфологічних змін в слизовій оболонці шлунка білих щурів у динаміці хронічної інтоксикації нітратом натрію. Аналіз репаративних процесів шлунку у динаміці загоєння експериментальної ацетатної виразки.

Дослідження стану окиснювального метаболізму у слизовій оболонці шлунка білих щурів у динаміці інтоксикації нітратом натрію. Аналіз репаративних процесів в слизовій оболонці шлунка білих щурів у динаміці загоєння експериментальної ацетатної виразки.

Major occlusive disease of the arteries, a major risk factors of atherosclerosis. Classification of diseases according to Fontaine-Pokrovsky. Features of obliterative endarteritis. Branches of the posterior tibial and the anterior tibial artery.

The study of the correlation of metabolic syndrome and non-alcoholic fatty liver disease. Steatal changes in the liver, which can act as an initiating component of the metabolic syndrome. Communication NAFTLD with hyperlipidemia noted by many researchers.

Role of IT in competence formation of future mid-level medical professionals. Analysis of nursing documentation methods. Role of nurses in improving health standards. Evaluation of health needs and care for the healthy and the sick by training community.

Frequency, anatomy, classification, diagnosis, and the most effective open methods of inguinal hernia’s operative therapy in adult patients. The recommendations of the Ukrainian association of surgeonsherniologists and the European European Hernia Society

The treatment of congenital hip dislocation in older children and adolescents as a problem of orthopedics, caused by a variability of anatomical changes and the degree of dislocation. Prospects for extra-articular operations on the pelvic and femur.