The root canal treatment usually fails when the treatment is carried out inadequately. The aetiology of the failure of root canal treatment, particularly in cases of well-treated root canals. Indications for the treatment of endodontic failures.

The percent time pH is less than 4 in the distal esophagus, termed the acid exposure time - the most relevant and reliable parameter on ambulatory reflux monitoring. Heartburn like a separate entity that warrants a multimodal management distinct.

Analysis of the distribution of polymorphic variants of genes by SNP F2 G20210A, F5 G1691A and MTHFR C677T among the Ukrainian population. Analysis of SNP alleles among unrelated individuals by PCR and RFLP analysis. Evaluation of combined genotypes.

Allergen immunotherapy-mechanism of action. Allergen immunotherapy adherence: persistence and consistency. Economic impactof medication non-adherence. Research studies on improving ait adherence: key findings. Literature review of persistence of ait.

The study of molecular mechanisms of regulation of biologically active molecules. Role of serine proteinases in the regulation of physiological and pathogenic processes. The localization, functional role and manifestations of allosteric region.

Investigation of genes involved in the processes of ensuring resistance to desiccation in Polypedilum vanderplanki. Comparison of survival, expression and splicing between knockdown and wild-type cells. Analysis of the dehydration-rehydration cycle.

Gastro-esophageal reflux disease as a condition which develops when the reflux of gastric content causes troublesome symptoms or complications. Grading of recommendations assessment and evaluation system for the quality of evidence for guidelines.

The nickel–titanium alloy Nitinol has been used in the manufacture of endodontic instru-ments in recent years. Construction of root canal instruments that utilize these favourable characteristics to provide an advantage when preparing curved canals.

Medical history progressing swelling in the canine region of the edentulous mandible. Treatment of tumors with a combination of chemotherapy and radiotherapy. Diagnosis of peri-implant bone loss around the mandibular implant with panoramic radiographs.

The study of the anaerobic capabilities of girls in the mountainous regions of Zakarpattia. Effect on the physiology of the body of a long stay at a very high altitude. Indicators of anaerobic productivity of the body’s energy supply in healthy girls.

Small animal models of osteoarthritis are suitable for preclinical investigations of OA pathogenesis: its genetic and molecular mechanisms; large animal allow to investigate biomechanical changes of the joint and to provide intraarticular interventions.

The data of cracked teeth were collected and analyzed according to the restorative material and the classification of the restoration, clinical symptoms, the location of the tooth in the jaw, the direction of the crack line, and the treatment result.

It has carried out detection and analysis of 17p11.2 chromosome region rearrangements in CMT1 patients from Ukraine. It has been shown the association with HNPP clinical phenotypes may be used in differential diagnosis of this type of polyneuropathy.

The aim of the work was to analyse biosynthetic gene clusters (BGC) of Bacillus velezensis ONU 553 based on bioinformatics approach. Analysis of biosynthetic gene, bacteriocin, and antibiotic resistance gene clusters using antiSMASH, Bagel4, respectively.

Carrying out a comprehensive analysis of physical form from the point of view of maximum oxygen consumption and body mass index, body fat percentage among male and female students. Development of linear regression equations for estimating body density.

Digestive problems due to junk food. The use of recording electrical activity due to gastric motility using surface electrodes is cutaneous. Applying the wavelet transform to the EGG signal to find the frequency deviation from the power estimation graph.

The causes of degradation of articular cartilage. Analysis of the anti-inflammatory properties and the sequence of use of chondroprotective drugs. The study of effectiveness of the cumulative method of introducing glucosamines and chondroitin sulfates.

Analysis of modern methods of diagnosis and treatment of cardiovascular diseases. The impact of imaging methods on the accuracy of diagnosis. Integration of digital technologies, artificial intelligence, minimally invasive procedures, telemedicine.

Treatment of unstable proximal femoral fractures: comparison of the proximal femoral nail antirotation and nail. Analysis of perioperative blood loss in treatment for femoral intertrochanteric. The effect of clopidogrel blood loss in hip fracture surgery.

The research urgency is caused by necessity of studying the students somatic health level due to a sharp deterioration of health state during the last decade. The aim of the investigation is studying the dynamics and nosological forms of students.

Producing countries classification, providing the population of Ukraine effective, qualitative and safe drugs. General characteristics of the methods of treatment of nicotine addiction. Pharmaceutical companies who supply antinicotine medications.

Research of the main tendencies of the pharmaceutical market affecting the activity of manufacturing pharmaceutical enterprises are appearance of new medicines, expansion of the assortment. Development of pharmaceutical enterprises in the conditions.

Dangerous emotional and cognitive disorders after transient ischemic attacks, priority actions to overcome the aggravating consequences of the attack. Correct assessment of the patient's condition is a critical element in preventing complications.

Analyzes the opinions of health care managers of all levels regarding the transformation of primary and secondary health care. The questionnaire proposed made it possible to study the individual assessment of the state of health of the population.

Obesity is a global epidemic. Obesity is on the rise in developing countries due to changes in lifestyle. This study aimed to compare body image problems and social-physical anxiety in obese and normal-weight adolescents by examining the moderating role.

Research of the pace of development of the pharmaceutical industry for the synthesis of new chemical compounds. Standardization of treatment and prevention of diseases. The rise of drug allergies, which often have serious consequences for human health.

Classification, signs and symptoms of angina. The pathophysiology, diagnosis and epidemiology. Imbalance between the heart's oxygen demand and supply. Definition the nature of the coronary lesion. Increase in the blood pressure and the pulse rate.

The concept of Ankylosing spondylitis. Signs and symptoms, etiology and pathophysiology. Diagnosis of disease and it prognosis. Progressine deformity over a period of 36 years. Treatment and methods of control and prevention of ankylosing spondylitis.

Causes of delivery anomalies. Consideration of pathological preliminary period, dis-coordinated labors, excessive labor, clinical manifestations, peculiarities of diagnosis and treatment. The impact of work on the anomalies of the fetus and newborn.

Orthodontic treatment using the braces system of active self-ligation of the direct arc technique, with the use of the anthropometric system at the stage of adjustment. Evaluation of the effectiveness of orthodontic treatment according to the ABO system.