Оптимизация предгравидарной подготовки женщин, страдающих хроническим пиелонефритом

Анализ особенностей клеточного и гуморального иммунитета у женщин с хроническим пиелонефритом в предгравидарном периоде и в динамике гестации. Оценка клинико-иммунологической эффективности эриксина и его влияния на морфофункциональное состояние плаценты.

Рубрика Медицина
Вид автореферат
Язык русский
Дата добавления 24.05.2018
Размер файла 53,8 K

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Область применения: Акушерство и гинекология.

RESUME

Thesis of Abdullaueva L.F. on the theme: “Optimization of before pregnancy preparing of women, suffering chronic pielonephrit” on competition of the medical sciences on speciallity 14.00.01. - an Obstetrics and gynecology subjects.

The key words: pregnancy, pielonephrit, immunity, Eryxin.

The object of the study: 80 women of reproductive age and 110 pregnants, suffering chronic pielonephrit.

The purpose of the study: to value the Eryxins clinic-immunological efficiency in complex therapy before pregnancy preparing of women and in decreasing of obstetrics and perinatal complications in pregnants suffering chronic pielonephrit.

Methods of the study: clinic-laboratory, ultrasonic, sonocardio-graphic, morphological, immune status study.

The results achieved and their novelty: Pielonephrit is an often disease of urine genital system among pregnants and at last year's is noted trend to growing of this disease from 41,7% to 48,9% with increasing of the first time revealed pielonephrit in pregnancy to 2,8 time.

In nonpregnat's and pregnant's with chronic pielonephrit is revealed the secondary immune deficit characterized by nonspecifical changes in immune system, expressing of Т-cell immunity, IRI, nonspecifically resistance factor's, humoral immunity activation with increasing CIC and autoimmune process's in organism. The traditional therapy is not rendered sufficiently correction to immune system, that's why exacerbation of chronic pielonephrit is noted in 85,4% cases. The results of investigation are indicated about primary of before pregnancy complex therapy of pielonephrit with Eryxin, which promote to smooth over the inflammatory process and improved the functional state of renals, prevent the progress of inflammatory process. Including the Eryxin in second trimestr to complex therapy on pregnants promotes for stabilization of immune system indexes reduces the frequency of deseases relapse for 4 time, develop the compensation adaptation, reactions in placenta, directed for ensuring of necessary conditions for foetus development, prevent and increase the obstetrical and perinatal complications in 2 and 3 time.

Practical value. The devised complex of diagnostical and treatmet prophilactic measures promote to pathogenical substantiate of before pregnancy preparing of women with pielonephrit, including Eryxin, increase the obstetrical and perinatal pathology in 2 and 3 time.

Degree of embed and economical efficiency: For results of thesis's was published 1 methodical recommendations, which were introduced on clinics of Obstetrics and gynecology scientifically practical medical center and it's 4 branches.

The region of application: Odsterics and gynecology.

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