ó㳺í³÷íà îö³íêà òà ðåãëàìåíòàö³ÿ êîìá³íîâàíî¿ ä³¿ äîäåöèëáåíçîëñóëüôîêèñëîòè, íàòð³ºâî¿ ñîë³ áåíçîëñóëüô³íîâî¿ êèñëîòè ³ ôëîðîãëþöèíó ó âîä³ âîäîéìèù
Âèâ÷åííÿ ³çîëüîâàíî¿ ³ êîìá³íîâàíî¿ ä³¿ äîäåöèëáåíçîëñóëüôîêèñëîòè, íàòð³ºâî¿ ñîë³ áåíçîëñóëüô³íîâî¿ êèñëîòè ³ ôëîðîãëþöèíó íà ïðèñìàê, çàïàõ âîäè, ï³íîóòâîðåííÿ, ñàí³òàðíèé ðåæèì âîäîéì. ¯õ òîêñè÷í³ñòü äëÿ îðãàí³çìó â óìîâàõ ñàí³òàðíîãî åêñïåðèìåíòó.
| Ðóáðèêà | Ýêîëîãèÿ è îõðàíà ïðèðîäû |
| Âèä | àâòîðåôåðàò |
| ßçûê | óêðàèíñêèé |
| Äàòà äîáàâëåíèÿ | 24.06.2014 |
| Ðàçìåð ôàéëà | 97,2 K |
Îòïðàâèòü ñâîþ õîðîøóþ ðàáîòó â áàçó çíàíèé ïðîñòî. Èñïîëüçóéòå ôîðìó, ðàñïîëîæåííóþ íèæå
Ñòóäåíòû, àñïèðàíòû, ìîëîäûå ó÷åíûå, èñïîëüçóþùèå áàçó çíàíèé â ñâîåé ó÷åáå è ðàáîòå, áóäóò âàì î÷åíü áëàãîäàðíû.
Ñìåñü îáåèõ âåùåñòâ ñîîòâåòñòâåííî â êîíöåíòðàöèÿõ 50 è 40 %, 25 è 20 % ïðîÿâëÿåò êîæíî-ðåçîðáòèâíîå äåéñòâèå. Ïðîâåäåííûå èññëåäîâàíèÿ ñâèäåòåëüñòâóþò, ÷òî êîìáèíàöèÿ äîäåöèëáåíçîëñóëüôîêèñëîòû è íàòðèåâîé ñîëè áåíçîëñóëüôèíîâîé êèñëîòû îáëàäàåò ñåíñèáèëèçèðóþùèìè ñâîéñòâàìè íà îðãàíèçì ìîðñêèõ ñâèíîê ïðè ïåðîðàëüíîì ââåäåíèè.
Ïîäîñòðûé îïûò íà áåëûõ êðûñàõ ïîïóëÿöèè Âèñòàð ïîêàçàë, ÷òî ñìåñü äîöåöèëáåíçîëñóëüôîêèñëîòû è íàòðèåâîé ñîëè áåíçîëñóëüôèíîâîé êèñëîòû èìååò òîêñè÷åñêîå âëèÿíèå íà êðàñíóþ êðîâü, àêòèîêñèäàíòíóþ ñèñòåìó, óñèëèâàåò ïåðåêèñíîå îêèñëåíèå ëèïèäîâ è ýíäîãåííóþ èíòîêñèêàöèþ, îòðèöàòåëüíî âëèÿåò íà áåëêîâûé, óãëåâîäíûé è ëèïèäíûé îáìåíû, óãíåòàåò èìóííóþ ðåçèñòåíòíîñòü îðãàíèçìà ïîäîïûòíûõ æèâîòíûõ.
Íåáëàãîïðèÿòíîå âëèÿíèå ñìåñè äîäåöèëáåíçîëñóëüôîêèñëîòû è íàòðèåâîé ñîëè áåíçîëñóëüôèíîâîé êèñëîòû â óñëîâèÿõ ïîäîñòðîãî îïûòà ïîäòâåðæäàåòñÿ ðåçóëüòàòàìè ìîðôîëîãè÷åñêèõ èññëåäîâàíèé. Íàèáîëåå âûðàæåííûå èçìåíåíèÿ íàáëþäàëèñü â ïå÷åíè, ïî÷êàõ, òîíêîì è òîëñòîì êèøå÷íèêå, ñåðäöå.
Òîêñèêîëîãè÷åñêèå èññëåäîâàíèÿ ñâèäåòåëüñòâóþò, ÷òî äîäåöèëáåíçîëñóëüôîêèñëîòà è íàòðèåâàÿ ñîëü áåíçîëñóëüôèíîâîé êèñëîòû îáëàäàþò ìåìáðàíîòðîïíûì äåéñòâèåì. Ýòè ñîåäèíåíèÿ ïðîÿâëÿþò âûðàæåííîå ìåñòíî-ðàçäðàæàþùåå äåéñòâèå ïðè ââåäåíèè èõ ñìåñè â êîíúþíêòèâàëüíûé ìåøîê ãëàçà êðîëèêîâ.
Êëþ÷åâûå ñëîâà: äîäåöèëáåíçîëñóëüôîêèñëîòà, íâòðèåâàÿ ñîëü áåíçîëñóëüôèíîâîé êèñëîòû, ôëîðîãëþöèí, ãèãèåíè÷åñêàÿ ðåãëàìåíòàöèÿ, çäîðîâüå íàñåëåíèÿ, àëëåðãåííûå ñâîéñòâà, êîæíî-ðåçîðáòèâíîå äåéñòâèå.
SUMMARY
Nadkevich N.L. Hygienic evaluation and regulation of the combined action of dodecilbenzenesulphinic acid, sodium salt benzenesulphinic acid and phloroglucinol in water of ponds. - Manuscript.
This is for Candidate of Medical Science in speciality 14.02.01 - hygiene.
Ukraine scientific hygiene center, Health protection Ministry of Ukraine, Kiev, 2002.
The dissertation deals with the problems of the hygienic regulation of the dodecilbensolsulphid, bensolsulphid sodium and phloroglucin as well as their combinations in the ponds water for the sanitary household application.
It was found that all investigated substances have negative effect on the organoleptic properties of water its pits self-purification, behave as skin-absorbtim and allergic, have toxic effeet on the liver, kidness, heart and alimantary canal. The limit concentrations of dodecilbensolsulphid, bensolsulphid sodium and phloroglucin in the ponds water is reasoned. Binary mixture of dodecilbensolsolsulphid and phloroglucin is potential under the conditions of urgent and suburgent experiments, as well as influences the organoleptic properties of water.
Key words: hygienic regulation, water quality, population health, allergic properties, skin-absorbtion.
Ðàçìåùåíî íà Allbest.ru
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